Sentence examples for binds to the adaptor from inspiring English sources

Upon antigen-binding, this region is exposed and binds to the adaptor protein Nck [ 11, 12].

SOS participates by binding to Grb2 (growth factor receptor-bound protein 2) that in turn binds to the adaptor LAT (linker for activation in T cells) [5].

Once released from the mitochondria into the cytosol through MOMP, cytochrome c binds to the adaptor molecule APAF-1, causing it to oligomerise and form a heptameric structure called apoptosome [54].

We have examined the contribution of BCR sequences to the inhibition of BCR-ABL nuclear import, specifically focused on the BCR Tyr177 phosphorylation site and the BCR R91ASASRP97 region that binds to the adaptor protein 14-3-3-delta 14-3-3-delta 14-3-3-delta 14-3-3-deltarotein-protein interactions that might contribecause theseytoplasmic retention of BCR-ABL.

Phosphorylated CagA directly binds to the adaptor proteins Crk and CrkL [ 72]. 56.

Phosphorylated paxillin binds to the adaptor protein Crkll, which, in turn, binds to an atypical Rac GEF complex, DOCK180/ELMO, and p130Cas to stimulate spreading by activating Rac1.

CBC is composed of a Cullin scaffold bound to the adaptor proteins Elongin B and C, which in turn bind to the substrate receptors suppressor of cytokine signaling (SOCS) or von Hippel-Lindau (VHL) [ 6].

Presumably, some degree of disorder in the tether is required to allow different substrates to bind to the adaptor and be presented to the motor proteins in the correct orientation to be grabbed onto and unfolded.

The C-terminal proline-rich domain of Dab2 has been shown to bind to the adaptor molecule Grb2 and prevent its association with Sos, thereby decreasing activation of the Ras signaling cascade (Xu et al, 1998; Zhou and Hsieh, 2001).

The structure of the p53 C-terminus bound to the adaptor protein 14-3-3 14-3-3 14-3-3ntly described, providing a rationale for thasobeenved stabilizing effect of 14-3-3 binding [ 36].

Recent transgenic experiments have shown that K17 can bind to the adaptor protein 14-3-3σ 14-3-3σ 14-3-3σcell growth and sinfluencesse keratinocells by regrowthng protein synthesis (Kim et and 2006).