Sentence examples for binds to the active from inspiring English sources

The combined interpretation of the binding and activity data suggests that XOS binds to the active site of TrCel7A and hence exerts competitive inhibition.

ROCK is activated when it selectively binds to the active GTP-bound form of Rho, after which activated ROCK interacts with the actin cytoskeleton to promote stress fiber formation and the assembly of focal contacts [ 13, 14].

Antagomirs, an example of miRNA antagonists, can be applied to allow gain of function within diseased states by introducing a chemically modified RNA that binds to the active miRNA of interest to inhibit its activity and rescue the repression of its target.

First, susceptibility to sub-lethal doses of two antibiotics was examined (i) chloramphenicol, a peptidyl transferase inhibitor that targets the translation machinery and, (ii) amoxicillin that irreversibly binds to the active site of penicillin-binding proteins (PBPs) involved in cell wall biosynthesis.

After translocation, the incoming NTP binds to the active site with a binding rate constant k 2 and a dissociation rate constant k −2.

After Rho has been activated by geranylgeranylation, its downstream effector ROCK is activated when it selectively binds to the active GTP-bound form of Rho.

42 PPG binds to the PBD of Plk1, while Poloxin and Thymoquinone bind to the active, ATP-binding site of Plk-1.

Competitive inhibition occurs when molecules very similar to the substrate molecules bind to the active site and prevent binding of the actual substrate.

Most competitive inhibitors bind to the active site, preventing substrate binding; thus, it is likely that feruloyl amide binds to the glutamine-binding site in PurF.

Binding to the active site on the receptor regulates receptor activation directly.

The Birc (or IAP) proteins are classical cellular inhibitors of caspases, which bind to the active site of caspase and inhibit caspase activity [48].