When chilli peppers are the source of the capsaicin, there isn't any actual tissue damage; but because it binds to the TRPV1 receptor, the brain is tricked into believing that the tongue truly is on fire.
Indeed, once it has been released in the systemic circulation, AVP binds to the V2 receptor, a 7-transmembrane domain protein coupled to G-proteins which is located on the basolateral surface of the collecting ducts.
18F-nifene binds to the α4β2 receptors in thalamic and extrathalamic regions in rat microPET studies.
CXCL12 binds to the CXCR4 receptor, a multi-facetted molecule which tightly mirrors CXCL12 functions in homeostasis and disease.
The octapeptide hormone angiotensin II is the active product of RAS which causes vasoconstriction when binds to the AT1 receptor.
PACAP and VIP are functionally linked as both peptides bind to the VPAC1 and VPAC2 receptors with equal affinity, but PACAP also selectively binds to the PAC1 receptor [2].
Polysaccharides such as hyaluronic acid are used as a targeting moiety of the drug conjugates or nanoparticles for cancer therapy since it specifically binds to the CD44 receptor [31].
When it binds to the CB2 receptor, it helps with inflammation and pain relief.
Specifically the drug binds to the 5-HT2A receptor, which is also the same target for LSD and a range of antipsychotic drugs.
When someone smokes weed, the THC binds to the CB1 receptors in their brain, which leads to a huge increase in appetite.
