Sentence examples for binds to specific sequences from inspiring English sources

Exact(8)

Puf family members are usually identified by the presence of eight tandem Puf repeats of ∼35 39 amino acids [8] and the repeat binds to specific sequences in the 3' untranslated region (UTR) of a target mRNA.

A transcription factor is defined as a regulatory protein that binds to specific sequences in DNA and affects transcription of specific genes.

One type of recombinase binds to specific sequences of DNA bases and uses an amino acid in the enzyme usually serine or tyrosine to break and rejoin the DNA strands.

In cancer cell lines, Miz-1 binds to specific sequences termed initiator elements (INR) in the core promoters of its target genes and activates their transcription through recruitment of coactivators including the histone acetyltransferase (HAT) p300 and nucleophosmin [ 2- 4].

Upon activation, IκBα undergoes sequential phosphorylation by IκBα kinase and ubiquitination and degradation; the p50/p60 heterodimer is released and translocated to the nucleus, where it binds to specific sequences in the promoter regions of target genes [63].

The 1,25(OH 2D-VDR-RXR cOH 2D-VDR-RXRto specomplexequences in the promoter regions of target genes that are called vitamin D response elements (VDREs), leading to the promotion and modulation of the expression of the targeted genes.

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Similar(52)

NFE2L2 is a redox regulated transcription factor prominently expressed in Müller cells and astrocytes in the retina [ 8, 83] and binds to specific sequence elements in the 5′UTR of target genes.

Transcription factors are proteins which bind to specific sequences of DNA, called binding sites, enabling and controlling the expression of genes.

The DNA binding domain of ERs allows the receptors to bind to specific sequences in the promoters of estrogen-regulated genes.

R2R3 MYB genes tend to display limited homology (aside from the highly conserved DNA binding region), and the code by which R2R3 MYB genes bind to specific sequences has not been well elucidated [ 45, 48].

The activity of genes is governed by transcription factors, which bind to specific sequences of DNA units that lie close to the gene.

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