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Rather than binding directly to specific DNA sequences in the hly operon, Hha exhibits nonspecific DNA binding; therefore, it was proposed Hha binds to H-NS, which binds to specific regions of regulatory sequences in the hly operon [17].
These data suggest how the HCV IRES binds to specific regions of eIF3 to target the translational machinery to the viral genomic RNA and provide a framework for modeling the architecture of intact human eIF3.
Our results appear to corroborate a previous report indicating that α-crystallin binds to specific regions of DNA in mouse γD/E crystallin genes [45].
When Fur is bound to its iron (Fe2+) co-factor, it binds to specific regions in iron-regulated promoters called Fur Boxes and blocks the binding of RNA polymerase.
Here, we revealed that p53 binds to specific regions into the promoters of the genes relative to MVA pathway independently from SREBP1 and SREBP2 proteins.
In one of the loops (core loop), the two transcription factors BMAL1 and CLOCK form a complex that binds to specific regions of DNA called enhancer-boxes (E-boxes).
Similar(53)
The specific localization is mediated by RNA binding proteins, such as Staufen and Exuperantia, which bind to specific regions of the 3'-UTR of both Nanos and Bicoid and, via interactions with cytoskeleton-anchoring proteins and motor proteins, are translocated to their respective destination locations [ 11].
Activators bind to specific regions of the DNA in the upstream regulatory region, some very distant from the binding of the initiation complex.
For example, proteins that bind to specific regions of DNA act as transcription factors by activating or repressing gene expression of the DNA.
The paradigm for genome engineering shifted seemingly overnight in late 2009 with the discovery that TALEs proteins produced by Xanthamonas bacteria to regulate transcription in their host plant cells could bind to specific regions of DNA.
Unexpectedly, TEL-AML1 binds to specific promoter regions mostly distinct from AML1-bound promoter regions in murine cell line models, although binding seems to be, at least in part, mediated by the Runt DNA-binding domain as the consensus signal is enriched in direct targets over background and also over indirect TEL-AML1 targets defined here.
More suggestions(15)
binds to disordered regions
binds to regulatory regions
binds to hydrophobic regions
binds to methylated regions
binds to specific motifs
binds to specific sequences
binds to specific loci
binds to complementary regions
binds to genomic regions
binds to specific sialosaccharides
binds to other regions
binds to different regions
binds to specific mRNA
binds to specific receptors
binds to specific sites
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