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The negative pole of the dipolar water molecule binds to positively charged groups; the positive pole binds negatively charged ones.
The AuCl4 anion binds to positively charged functional groups, such as amino groups (NH2), on the algal surface.
Thus, ABCB1 preferentially binds to positively charged, amphipathic molecules and this suggests the involvement of acidic residues such as Asp and Glu in drug binding.
Negatively charged heparin binds to positively charged histones in the nucleosome complex and opens their architecture [ 88].
The three-dimensional structure and mutagenesis of EV71 suggest that PSGL-1 binds to positively charged amino acids located near the five-fold vertex via an electrostatic interaction.
It can therefore be understood that an excess of heparin binds to positively charged parts of the dendritic oligospermine before it displaces siRNA from a complex.
Similar(54)
It was suggested that salt's cation bound to positively charged lysozyme molecule with its hydrophobic group and at the same time cation's positive charge stabilised lysozyme secondary structure.
In similar fashion, proteins that have to bind to positively charged molecules have surfaces rich with negatively charged amino acids like glutamate and aspartate, while proteins binding to negatively charged molecules have surfaces rich with positively charged chains like lysine and arginine.
Molecular-docking simulations suggested that these sulfate clusters bind to positively charged, clamp-like regions on elastase that span the active site [48].
Among the anions that occur in PDB more than 100 times, 743 SO42− (743/948 = 78.5%) and 109 PO43− (109/148 = 73.6%) bind to positively charged residues, while some other anions less frequently bind with the charged residues.
Purification methods based on the fact that the large anion, DNA, can efficiently bind to positively charged resins provide high yield, however there is often contamination with genomic DNA.
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CEO of Professional Science Editing for Scientists @ prosciediting.com