Sentence examples for binds to its responsive from inspiring English sources
This activated molecule now binds to its responsive promoter and induces expression of the resistance gene, res.
Indeed, several reports demonstrate GATA3 transcriptional regulation of factors which have pivotal functions in cell cycle control, for example, p18 (ink4c) [ 51, 52] and cyclin D1 [ 53, 54] where GATA3 binds to its responsive element in the respective promoters.
By use of this system it was shown that when HIV-1 RevM10 is fused to the GAL4DB it tightly binds to its target RNA, the Rev responsive element (RRE) (65).
During hypoxia, HIF-1α protein is stabilized by a decrease in activity of prolyl hydroxylases, binds to its binding partner HIF-1β, and translocates to the nucleus to bind to hypoxia-responsive cis-elements [ 75].
The resultant heterodimer, HIF-1, binds to its cognate DNA sequence, the hypoxia-responsive element (HRE), and induces the expression of various factors such as vascular endothelial cell growth factor (VEGF; Norris and Millhorn, 1995; Forsythe et al, 1996; Semenza, 2001).
Binding of VDR to its responsive element induces expression of antimicrobial peptides (i.e. cathelicidin and β-defensin) with activity against S. aureus in vitro [ 10– 10].
Likewise, the MI-ER1 SANT domain functions in gene repression by interacting with Sp1 and interfering with its ability to bind to its cognate site on responsive promoters (Ding et al, 2004).
They mediate gene expression by binding to thyroid-hormone-binding protein, which binds to TH responsive element and regulates the transcription of different genes (Wu and Koenig 2000).
