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To understand how B. pseudomallei binds to its host cell surface, we have investigated several B. pseudomallei TAAs using a structural genomics approach [17], [18], [19], [20].
The phage recognizes and binds to its host, Escherichia Coli, causing the DNA in the head of the phage to be ejected through the tail into the cytoplasm of the bacterial cell.
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In this study, we show that the Cdom region in the SU from subgroup C feline leukemia virus (FeLV-C) forms a second receptor-binding domain that is distinct from its RBD, and which can independently bind to its host receptor FLVCR1, in the absence of RBD.
In another study, Rezende helped functionally characterize the specific fragments of the cell surface protein, Als5p, that allows the pathogenic fungus, Candida albicans, to bind to its host.
Following delivery to the target site, the virus binds to the host cell, enters the cytoplasm and releases its payload into the nucleus.
Factor H, the major inhibitor of the AP of complement activation in the fluid-phase, binds to host cells and inhibits complement activation by its ability to interfere with the formation and activity of the alternative C3 convertase, C3bBb.
S1 recognizes and binds to host cell receptors, leading to the conformational changes of S2 that mediate viral fusion between the viral envelope and the host cell membrane.
LL-37 binds to host DNA [16].
Overall, these data illustrate that δ-toxin directly interacts with, and binds to, host AMPs.
However, ACT binds to host cells through the integrin CD11b/CD18 receptor, which does not associate with lipid rafts before cell activation has taken place [28].
The P2 domain is a hypervariable region that binds to host cell [ 13].
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CEO of Professional Science Editing for Scientists @ prosciediting.com