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Under inflammatory conditions, PL directly binds to its cell surface receptor, annexin II, which is expressed on activated monocytes/macrophages, DCs and keratinocytes, a critical initiating step in the pathogenesis of psoriasis in predisposed individuals.
The chemokine CXCL12 is an extracellular chemokine which binds to its cell surface receptor CXCR4.
In a classical IL-6 signalling pathway, cytokine IL-6 secreted by monocytes or macrophages binds to its cell surface receptor IL-6Rα.
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Hyaluronan interacts with several binding proteins and can be incorporated into the extracellular matrix or bound to its cell surface receptors.
Transferrin bound to its cell surface receptor is internalized by endocytosis, and has been well characterized as a classic marker for the perinuclear endocytic recycling compartment (ERC) [26].
We therefore hypothesized that serum IgE does not necessarily reflect total body IgE because in vivo IgE can be bound to its cell surface receptors FcεRI and CD23.
Both monomeric and heptameric CDTb bind to its cell surface receptor LSR (lipolysis stimulated lipoprotein receptor).
One study showed that Enterobacter cloacae SLD1a-1 wableble to reduce selenium (VI) (selenate), which was bound to its cell wall, to elemental selenium.
To understand how B. pseudomallei binds to its host cell surface, we have investigated several B. pseudomallei TAAs using a structural genomics approach [17], [18], [19], [20].
Lysophosphatidic acid (LPA) is a bioactive lipid that binds to its specific cell surface G protein coupled receptors (LPA1 6).
The extrinsic, death receptor-mediated pathway is activated at the cell surface when a specific ligand binds to its corresponding cell-surface death receptor.
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CEO of Professional Science Editing for Scientists @ prosciediting.com