Sentence examples for binds to its DNA-binding from inspiring English sources

The activated p53 binds to its DNA-binding consensus sequence that is present in its target genes [15].

The Hematopoietic Zinc Finger protein (HZF) that is induced by p53 and binds to its DNA-binding domain, facilitates p53-binding to cell cycle arrest target genes resulting in preferential cell cycle arrest [8].

The single initiation site model predicts that once a transcription factor binds to its DNA binding site, it remains bound for a long period of time, probably until an intracellular signal induces detachment [34].

When acetylated, PLZF binds to its DNA binding sites, and induces histone deacetylation and DNA hypermethylation followed by PLZF target genes repression.

The ΔMYCN protein contains a nuclear localization signal, a basic helix-loop-helix, and a leucine-zipper domain, which may serve to dimerize with MYCN or bind to its DNA binding site.

FOXO3a transcription factor is able to bind to its consensus DNA-binding motif - TTGTTTAC - in the promoter regions of several of these atrogenes, including Atrogin-1, LC3, Bnip3 and Gabarapl1 [ 13- 15].

These systems involve expressing GFP under the control of a minimal promoter such that GFP expression and fluorescence is observed only when a transcription factor is activated (i.e., when the transcription factor binds to its specific DNA binding sequence and induces expression from a minimal promoter).

Probably FRUR was partially inactivated in the presence of glucose, because fructose-1-phosphate and fructose-1,6-bisphosphate bind to FRUR and inactivate its DNA-binding capacity [ 43, 44].

In this model the p.G56R mutant protein binds to CRX, hinders DNA-binding of the CRX/NR2E3-p.G56R CRX/NR2E3-p.G56Racts as a repressor in trans.

According to their model, the LOV domain in the dark state binds to the bZIP DNA-binding domain.

Thus, we concluded that RelAp50 binds to sequences in vivo that resemble its DNA-binding preferences in vitro.