Sentence examples for binds to host from inspiring English sources
The virulence of Bacillus anthracis is critically dependent on the cytotoxic components of the anthrax toxin, lethal factor (LF) and edema factor (EF). LF and EF gain entry into host cells through interactions with the protective antigen (PA), which binds to host cellular receptors such as CMG2.
LL-37 binds to host DNA [16].
Overall, these data illustrate that δ-toxin directly interacts with, and binds to, host AMPs.
However, ACT binds to host cells through the integrin CD11b/CD18 receptor, which does not associate with lipid rafts before cell activation has taken place [28].
Factor H, the major inhibitor of the AP of complement activation in the fluid-phase, binds to host cells and inhibits complement activation by its ability to interfere with the formation and activity of the alternative C3 convertase, C3bBb.
In addition to enhancing recruitment of cells susceptible to infection, the stable ESAT-6/CFP-10 complex binds to host cells [13]; subsequently, modulating the host response favorably for the pathogen potentially via down-regulation of host cell killing mechanisms and immune cell activation [52].
PA binds to host-cell receptors and is cleaved by a furin-family protease to yield a 63 kDa species (PA63)[ 11] that self-assembles to form ring-shaped heptamers[ 12] and octamers.[ 13] These oligomers then form complexes with the cargo proteins (Kd∼1 n m) and are endocytosed.
Iron availability within cells is substantially different than in the extracellular milieu, where iron is scarce and often tightly bound to host iron-binding proteins (IBPs).
Previous structures of Crm1 bound to host cargo proteins have shown monomeric binding, so we sought to understand how Rev-RRE organizes a Crm1 dimer.
S. pneumoniae expresses a 75-kDa surface protein, Choline- binding protein A (CbpA) which has been shown to bind to host cells via secreted complement component C3 [ 20- 22].
Reverted unmutated ancestors of gp41-reactive antibodies derived from subjects acutely infected with HIV-1 frequently did not react with autologous HIV-1 Env; however, these antibodies were polyreactive and frequently bound to host or bacterial antigens.
