Sentence examples for binds to different regions from inspiring English sources
The interpretation of this result is that CENP-A binds to different regions in the two homologs, as in horses HSF-C and HSF-G.
These ligands may occupy very similar and overlapping binding regions, while the rest of the ligands bind to different regions within the QZ59-RRR-associated binding site.
The mechanisms underlying these effects suggest the participation of a great variety of proteins that bind to different regions of Cx43.
However, despite the common specificity for methylated histone H3, the three HP1 isoforms bind to different regions of the genome.
Most eukaryotes have at least three HP1 isoforms [1], which are conserved in overall structure but bind to different regions within the genome [2].
We demonstrate that these antibodies bind to different regions of LRP6 protein, and inhibition of signaling results from blocking Wnt binding.
As ryanoids and IpTxA were shown to bind to different regions in the RyR molecule [55], [56], our finding that protamine affects the action of both agents would suggest multiple sites of action or allosteric effects.
To determine whether full-length CHIP could bind to different regions of LRRK2, we co-transfected HEK293 cells with an expression vector for HA-tagged full-length CHIP (pHA-CHIP) and expression vectors coding for either myc-tagged ARM-ANK-LRR domains of LRRK2 (pMyc-AAL) or myc-tagged ROC-COR-kinase-WD40 domains of LRRK2 (pMyc-RCKW) (see Supplemental Figure S1).
10.7554/eLife.01754.012 Figure 8. Nef uses different surfaces to bind to different regions of AP-1 and AP-2.
We next investigated which region of the prion protein was present in these abberant PrPres fragments by probing with a panel of antibodies in the Western blot that bind to different regions of the prion protein (Technical Appendix).
The region defined by these mutations is a new co-chaperone interaction site of HSP90, as other well-known co-chaperones such as p23 (yeast Sba1) and AHA1 bind to different regions (see below).
