Sentence examples for binds to androgen responsive from inspiring English sources

2 Upon activation by androgens, AR translocates into the nucleus and binds to androgen responsive elements (ARE).

Androgens mediate their positive effect on transcription by binding to androgen receptor, which in turn binds to androgen response elements on the promoters of target genes [25].

In the presence of androgen, the androgen receptor (AR) undergoes phosphorylation, dimerization, and translocation into the nucleus, wherein it binds to androgen response elements (ARE) sites, resulting in the transcriptional activation of target genes [8].

In the nucleus, AR dimerises and binds to androgen-response elements to initiate the transcription of genes required for growth.

In hair follicles, the androgen binds to androgen receptors and exerts its effect directly [ 40].

These compounds bind to androgen receptor and show anti-androgenic activity towards androgen-dependent SC-3 cells with almost the same potency as the known anti-androgen hydroxyflutamide.

A class of drugs termed 'antiandrogens' can effectively treat prostate cancer because they bind to androgen receptors without activating them, thereby preventing androgens from binding.

Compound 41 also exhibited potent activity (IC50: 93 nM), and did not bind to androgen receptor, glucocorticoid receptor or mineralocorticoid receptor.

Classical signaling for testosterone to exert its effects is to bind to androgen receptor.

After interacting with androgen, the activated AR (androgen receptor) is translocated into the nucleus where it binds to AREs (androgen response elements) present in different target genes [ 5].

We went on to determine whether the effects of simvastatin on apoptosis are also applicable to androgen-responsive LNCaP cells.