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The corresponding protein region (the homeodomain), about 60 amino acids long, binds to a short stretch of DNA in the regulatory region of the target genes.
Unlike magainin 2 amide, a prototypical membrane disruptive AMP, buforin II amide adopts a poorly helical structure in membranes closely mimicking the composition of Gram negative bacteria, such as Escherichia coli, and binds to a short duplex DNA sequence with high affinity, ultimately forming peptide DNA condensates.
Instead, we demonstrate that the TCP domain of CPAP constitutes a novel proline-rich-motif (PRM) recognition-domain that specifically binds to a short target motif in STIL.
In fruit flies, dosage compensation relies on a male-specific molecular complex that binds to a short sequence of DNA found multiple times across the X chromosome (Conrad and Akhtar, 2011).
If Kaiso binds to a short region of highly methylated DNA that is not exactly in the middle of a peak having an overall low level of DNA methylation, then it is possible that a relationship between Kaiso binding and DNA methylation is obscured when the analyses are centered on the middle of the genomic regions identified by the peak-calling program.
Further, a region within the c-terminal RhoGAP-like domain of OCRL, in which several disease-causing mutations are found, binds to a short phenylalanine and histidine (F&H) motif found within the endocytic adaptors APPL1 and Ses1/2 (19, 19).
Similar(53)
The FP measurements indicate that MrkH binds the longer mrkA regulatory fragment (from −117 to +166) with a K d value of 3.07 μmol/L using the one site specific binding model, while MrkH binds to a shorter mrkA regulatory fragment (from −117 to −37) with a K d value of 8.24 μmol/L.
The system includes a DNA-cutting enzyme, Cas9, bound to a short RNA guide strand that is programmed to bind to a specific genome sequence, telling Cas9 where to make its cut.
Beside them in the mud, in a jumble of broken boards and torn plastic, lay a grave marker, a piece of wood the size of a checkbook bound to a short plastic pole.
In order to become competent for protein-primed initiation of reverse transcription, HP must first bind to a short RNA structure termed epsilon (HBV ε or Hε) on the 5′ end of pgRNA in a host chaperone-dependent reaction.
We first assessed the effects of the A481T mutation on Ago2 by determining the crystal structure of the mutant protein bound to a short target RNA bearing a t1A nucleotide (Table 3).
More suggestions(18)
binding to a short
binds to a central
binds to a specific
binds to a ribosome
binds to a pre-existing
binds to a cytosolic
binds to a GU-rich
binds to a different
binds to a lipopolysaccharide-binding
binds to a wide
binds to a conformational
binds to a precise
binds to a broad
binds to a proline-rich
binds to a pseudo-palindromic
binds to a bipartite
binds to a cell-surface
binds to a second
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com