Sentence examples for binds to a second from inspiring English sources

Both Geldanamycin (GA), which binds to the N-terminal ATP-binding site of the protein [ 22], and Novobiocin (NB), which binds to a second ATP-binding site on the C-terminal domain [ 23] are global Hsp90 inhibitors: that is, they are known to block both Hsp90 isoforms (α and β), which share about 80% homology, and maybe other factors.

Thereafter another part of the ET-1 molecule binds to a second distinct binding-site on the receptor (site L).

An elegant biochemical and structural study by Daniels and Weis showed that in addition to binding the N-terminus of LEF-1, β-catenin binds to a second region that spans the latter half of the protein (252 397) including the HMG DNA binding domain [ 24].

Only Pfr, induced by red light, binds to a second plant protein called PIF3.

Then the Cry oligomer binds to a second receptor.

Nox2, the catalytic subunit, is membrane-associated and binds to a second membrane protein, p22 phox.

BAFF and APRIL share two receptors – TACI and BCMA – and BAFF binds to a third receptor, BAFF-R.

In some cells and tissues, TGF-β also binds to a third cell surface receptor, TGF-β type III (TβR-III), which transfers TGF-β to TβR-II and TβR-I (26).

When HIV infects cells, gp120 first binds to the CD4 receptor on white blood cells and then "transitions" in such a way that hidden parts of the virus are exposed, allowing it to bind to a second receptor on the immune cells called CCR5.

The going theory for this--that antibodies generated by a first bout with dengue bind to a second strain, which helps it multiply in the immune cells--doesn't account for the internal bleeding and tissue damage, says Juthathip Mongkolsapaya of Mahidol University in Bangkok, Thailand.

Interestingly, in the several structures of bacterial Pdx1's that have been determined so far, sulfate, chloride or phosphate ions were shown to bind to a second site, referred to as P2, located at the hexamer interface of the Pdx1 dodecamer [17] [20].