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Hsp90 does not compete with CHIP for binding to the ubiquitin-modified domain, but rather, it binds to a region containing both the redox-sensing domain and the ubiquitin-modified domain of SENP3 and leads to abrogation of CHIP-mediated ubiquitin ligation.
A fragment of the invariant chain, residues 58 85, binds to a region proximal to the class II peptide binding groove and stabilizes occupancy of the class II invariant chain-associated peptide.
This is achieved by a protein called the lac repressor, which is produced by the repressor gene and binds to a region of the operon called the operator.
That Rnd3 binds to a region in the N-terminal of Syx sharing sequence similarity with the Raf-1 RBD is particularly interesting.
According to the predicted interaction between LhrA and lmo0302 mRNA, LhrA binds to a region overlapping the SD region as well as the start codon (Table 1).
Since LhrA binds to a region overlapping the start codon on the chiA mRNA (see Table 1), we performed a toeprint experiment to investigate the effect of LhrA on the formation of a translation initiation complex.
Similar(26)
The filter was mounted in VectaShield (Vector Labs, Burlingame, CA) with DAPI, a fluorescent molecule which strongly binds to A-T regions in DNA.
For most of the clones (Type I), binding was inhibited by L-Phe-Gly-Gly + substrate, indicating that they bound to a region of PLAP from where they were displaced by the specific inhibitor.
So-called in silico meaning "virtual"—screens were utilized to search extensive small-molecule chemical libraries for candidates predicted to bind to a region of a three-dimensional structure of a given macromolecule, such as the active site of an enzyme.
NNRTIs bind to a region that is not associated with the active site of the enzyme.
These interacting partners bind to a region located on the interdomain-connecting loop of each PCNA monomer [10] via their PCNA-interacting protein motifs (PIPs).
More suggestions(18)
binding to a region
extends to a region
binds to a protein
binds to a haem
binds to a linear
binds to a G-box
binds to a series
binds to a tumor
binds to a receptor
binds to a molecule
binds to a number
binds to a complex
binds to a WK-box
binds to a membrane
binds to a product
binds to a channel
binds to a range
binds to a site
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