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Despite this apparent promiscuity in substrate binding, each multidrug binding protein binds to a precise array of compounds.
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In the S. aureus multidrug binding repressor protein QacR, which binds to a diverse yet precise array of cationic compounds, it was predicted that glutamate residues lining the multidrug binding pocket would play a key role in drug binding affinity.
While microarray data may identify a core carbohydrate recognition sequence, the precise manner in which the protein recognizes and binds to a ligand remains undefined.
Gabapentin binds to a channel.
The researchers also pinpointed the precise location on the molecule--called the antigen-binding site--that allows it to bind to a specific foreign molecule or pathogen.
They only become legally bound to a transaction when a contract is formed and, with online purchases, the precise moment that happens is usually buried in the small print sent with the order confirmation.
As a result, the substrate does not simply bind to a rigid active site; the amino acid side-chains that make up the active site are molded into the precise positions that enable the enzyme to perform its catalytic function.
Yes, an emu bound to a lake, bound forever to walk the perimeter of the lake.
may be asked what precise response he would make to a precise provocation.
The knowledge thus collected is bound to be precise if not necessarily revealing.
In any case, our ultimate goal was to find a reliable upper bound rather than a precise dating.
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