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GIPC (homologous to GLUT1 C-terminal-binding protein, SEMCAP-1 and synectin) binds to a number of transmembrane receptors such as the LDL receptor megalin [92], the human lutropin receptor (LHR) [93] and the β-1 adrenergic receptor [95] and it is likely that myosin VI and GIPC are involved in the endocytosis of these receptors [96].
We have discovered that microcystin binds to a number of these proteins in vivo and that the binding is strongly enhanced under high light and oxidative stress conditions.
IR-phosphorylated IRS5 binds to a number of SH2 domain-containing proteins, that are distinct from those associated with IRS1.
Oxidized LDL, when free, binds to a number of cell-surface receptors, including scavenger receptors SR-A and CD36 which are the critical contributors to modified lipoprotein uptake in macrophages [1], [31], [32].
The major CfaB subunit of CFA/I binds to a number of non-acid glycosphingolipids, including glucosylceramide, lactosylceramide with phytosphingosine and/or hydroxy fatty acids, neolactotetraosylceramide, gangliotriaosylceramide, gangliotetraosylceramide, the H5 type 2 pentaglycosylceramide, the Lea-5 glycosphingolipid, the Lex-5 glycosphingolipid and the Ley-6 glycosphingolipid.
Each of these respective regions binds to a number of proteins.
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ChIP-qPCR analysis showed that RUNX1 was indeed bound to a number of tested p63 binding sites with the RUNX motif (Fig 4B; Supplementary Table S8B), indicating that RUNX1 can cooperate with p63 in epidermal cells.
In addition to binding PIP2, we show that NaD1 is also able to bind to a number of other phospholipids.
Members of the IRF family of transcription factors are known to bind to a number of consensus sites, as shown for the DNA-binding domain of IRF1 (Fig. 1B).
To understand how omega-3s curb inflammation, Jerrold Olefsky, an endocrinologist at the University of California, San Diego, and his colleagues trawled through the data on a family of proteins called G protein-coupled receptors, which can bind to a number of different fatty acids.
Most galaxies in the Universe are gravitationally bound to a number of other galaxies.
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