Sentence examples for binds to a major from inspiring English sources

Why MLL1 protein binds to a major fraction of gene promoters but with limited functions is still unknown at this moment.

Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but it is specific for the class I MHC protein.

With the advent of new display technologies and TCR formats for in vitro engineering, it should be possible to generate high-affinity TCRs against virtually any peptide antigen that is shown to bind to a major histocompatibility complex (MHC) molecule (e.g. peptides derived from viral antigens or from self proteins that are associated with the transformed phenotype).

MAb 155 has been described to bind to a major epitope of the cytoplasmic side of the α-subunit [ 25].

7 9 10 Theoretically, the administration via a tolerogenic route of peptides that mimic the naturally processed antigen when bound to a major histocompatibility complex (MHC) molecule would induce peptide-specific tolerance, a scheme whereby peripheral autoreactive T and, possibly, B cells would be deviated or suppressed via various mechanisms, including the involvement of regulatory T cells.

Particularly, E6 protein has a central role as a carcinogen factor because it binds to p53, a major tumor suppressor protein, inducing its degradation [ 4].

To activate T cells, fragments of molecules that provoke an immune response called antigens must be bound to a 'major histocompatibility complex' (MHC) and presented to these cells.

Already amphotericin B binds to ergosterol, a major component of the cellular membrane of Leishmania, forming transmembrane channels that release monovalent ions (K+, Na+, H+ and Cl−) leading to cell death [ 207].

A major step in identifying potential T-cell epitopes involves identifying the peptides that bind to a target major histocompatibility complex (MHC) molecule.

One major puzzle is how Hsp70 binds to a protein to fold it up.

Clegg's personal ratings also make gloomy reading for Lib Dems before a conference where his leadership is bound to be a major subject of discussion.