Sentence examples for binds to a high from inspiring English sources
In cases where the target binds to a high molecular weight interactor protein, we monitor changes in the NMR spectrum of the free target since only this species gives rise to visible peaks.
This optimized fusion protein toxin binds to a high- or intermediate-affinity receptor.
IL-33 is a ligand that binds to a high affinity receptor family member ST2 [ 33].
Perhaps one (explanation would be that the transition from high to low affinity is most likely to occur before the linker moves from a post to pre-powerstroke position. That is, ATP binds to a high affinity, post-powerstroke dynein. A rearrangement occurs that leads to a low affinity, post-powerstroke dynein (that releases from MTs).
Insulin actions are initiated when insulin binds to a high-affinity heterotetrameric transmembrane protein receptor that is present in all mammalian cells [ 22].
They showed that RovA could bind to a high AT abundance region with a high occurrence of poly(AT) stretches, and they did not find a strong characteristic of palindromic sequences in the inv and rovA promoters recognized by RovA.
The background br is an offset due mainly to unspecific binding of labeled CaM to the glass surface which was determined using a labeled CaM bound to a high affinity CKII(290 312)* peptide without a Cystein residue.
As already reported, a high MMP activity is not consequently bound to a high invasive potential because an extensive uncontrolled ECM-degradation can impede cell invasion due to a lack of required matrix components (Ruoslahti, 1992; Montgomery et al, 1994).
Previous studies showed while Gcn5 is bound to a high proportion of genes in S. pombe growing on rich media, it is requested for the expression of only a few of its binding targets [ 27, 28].
From this set, three target proteins were chosen that bind to a high number of ligands in the PDB, have a low number of native metabolic substrates as annotated in iJO1366, and for which there is structural coverage in the GEM-PRO of the individual proteins, protein complexes, and catalytic sites.
We recently reported that florbetaben, PIB and florbetapir all bind to a high-affinity binding site in postmortem AD brain tissues [ 12], demonstrating their reliability for detecting fibrillar Aβ deposits.
