Each PIP binds to a distinctive set of effector proteins and, thereby, regulates a characteristic suite of cellular processes, including membrane trafficking, cell survival/growth, cell division, and cellular motility [ 28] (See also Figure 5).
Notably, Asn34 and His34 each bind to A and G in different ways, which provides the structural basis for the distinctive recognition strengths revealed by genetic studies (Streubel et al., 2012).
Gabapentin binds to a channel.
Yes, an emu bound to a lake, bound forever to walk the perimeter of the lake.
It all added up to a distinctive group sound.
The latter has given rise to a distinctive recent literature.
This gives rise to a distinctive bushy, forward-angled spray.
Endostatin binds to at least two distinctive sets of molecules on the endothelial cell surface, α5 β1/ αv β3 integrin (Rehn et al, 2001; Wickstrom et al, 2002) and glycosyl-phosphatidylinositol (GPI) anchored heparin sulphate proteoglycan (HSPG), or glypican (Karumanchi et al, 2001).
In contrast to inhibitors that bind to distinctive enzyme active sites, molecules targeting protein surface topologies have been underexploited in drug development.
Hirano bodies are differentiated from these other actin aggregates by their eosinophilic nature, ability to bind to phalloidin, and distinctive ultrastructure [ 47, 8, 7, 45].
He said he had no memory of tying he up, but when found she was bound in a distinctive way -- with her shirt looped around her neck and used to gag her and tie her wrists close to the neck, a method he had used before and was a kind of trademark.
