Sentence examples for binds to a different from inspiring English sources
We initially utilized compounds 30 and 32, because these compounds were more effective in cell-based assays, but we also included 20 and 42, which were previously reported to be active against CDK9, and the known tankyrase inhibitor XAV939 1. Compound G007-LK, which binds to a different location in the NAD+ binding groove, was also studied in parallel32.
A second T-cell-related antibody, which binds to a different immune-suppressing protein, PD1, is being tested in smaller clinical trials.
To complicate matters, as Andreasson has previously shown, PGE2 does good things when it binds to a different receptor, EP4, found on nerve cells and the endothelial cells that line our blood vessels.
What is the type of inhibition that occurs when an inhibitor binds to a different part of the enzyme and changes the active site shape?
Altogether, the NMR data indicate that HMA binds to a different site compared to the one that adamantane compounds bind to.
In our other study [14], we showed that the HER2 Affibody binds to a different epitope of the HER2 receptor than the therapeutic epitope targeted by such widely used monoclonal antibodies as trastuzumab or pertuzumab.
The remit could appear in letters of gold at the top of the Memorandum and Articles and it would make no difference to a chief executive bound to a different master.
The XylC xylose complex crystal (with 200 mM xylose) shows, in addition to the active-site bound xylose molecules (coloured red), 31 other molecules (six observed at the dimer interface) of bound xylose (coloured green), which correspond to nine binding sites consistently present in each monomer (plus one bound to a different site in monomer D, coloured blue).
It was recently reported that Oct4 may preferentially bind to a different motif with consensus ATGCGCAT when not binding near Sox2 Masonn et al., 2010).
These anti-CD22 mAbs bind to a different epitope than does HB22.7, do not block ligand binding, and do not have functional effects [ 12].
It is noteworthy that the displacement experiments with HSA site I and II markers, demonstrated that 4 6 bound to a different site than that of AZT and 1 3.
