Phthalate monoesters were associated with hormones related to Leydig cell function.
Furthermore, our Leydig cell preparations expressed IL-6 mRNA, similar to Leydig cells obtained from younger donors (Cudicini et al., 1997).
Lymphatic spaces between seminiferous tubules and adjacent to Leydig cells (L) clusters are clearly defined.
For the Leydig cell aging group, 50 μM H2O2 and 100 μM FeSO4 solutions were added for 8 hours to Leydig cells that had been cultured for 48 hours in the incubator.
In the testes, LH binds to receptors on Leydig cells, stimulating synthesis and secretion of testosterone [ 29].
In the testes, Luteinizing hormone (LH), a gonadotrophin, which binds to receptors on Leydig cells, stimulating synthesis and secretion of testosterone.
In addition to controlling Leydig cell number, AR in adult Leydig cells has been postulated to control adult Leydig cell maturation (19, 22).
To our knowledge, COUP-TFII is the first identified transcription factor intrinsic to the Leydig cell, and plays an essential role in progenitor Leydig cell maturation.
50 Several LHCGR mutations have been reported to cause Leydig cell hypoplasia.
The increase in testosterone production occurred at lower concentrations of AM than those demonstrated to increase Leydig cell numbers.
