Sentence examples for binds in the active from inspiring English sources

In the autoinhibited structure of IRK, Tyr1162 within the activation loop binds in the active site in a position similar to the tyrosine of a peptide substrate.

These results are consistent with a two-site mechanism in which one molecule of SR RS2) freely binds outside the active site causing activation of SR ΔRS2) phosphorylation and a second molecule binds in the active site causing inhibition (Scheme 3).

A well-ordered L-arginine binds in the active site of the catalytic domain.

Docking studies revealed that compound 8 and 11 efficiently binds in the active site cavity of CA IX by forming sufficient numbers of H-bonds and van der Waals interactions with active side residues.

Lysine binds in the active site as an aldimine adduct of PLP.

UDP- S-GlcNAc binds in the active site of XcOGT (Fig.  2a).

The co-crystal structure reveals that the inhibitor binds in the active-site cleft, irreversibly modifying the active-site cysteine; however, the catalytic histidine is still misaligned as seen in the native structure, suggesting that the inhibitor binds to an inactive form of the enzyme.

However, without an ATP bound in the active site and a distorted phosphate-binding loop, to predict the importance of that lysine residue in MSK1 was difficult.

For different families of chitinolytic enzymes, the number, type, and position of substrate atoms bound in the active site vary, resulting in different substrate-binding specificities.

T125 and H217 reside in the peptide-binding β-sheet and are positioned near a Rin4 Thr bound in the active site.

In binding mode T2, and in contrast to 6, the S enantiomer was bound in the active site.