Sentence examples for binds at the cell from inspiring English sources

Alternatively, secreted PCSK9 binds at the cell surface to the first epidermal growth factor-like repeat (EGF-A) of LDLR [ 5, 6].

As one specific example, analysis of insulin signaling has shown that in a cell that is not being stimulated by insulin PTP1B actively blocks intracellular insulin signaling pathways, whereas when insulin binds at the cell surface, H2O2 is immediately produced, PTP1B is oxidatively inactivated, and insulin signaling is initiated.

At the molecular level, galectin-8 binds at the cell surface of osteoblasts to the low-density lipoprotein receptor-related protein 1 (LRP1) (Grey et al., 2004) and the mannose receptor C, type 2 (MRC2) (Engelholm et al., 2009) that negatively and positively regulate galectin-8 function, respectively.

To strip-off lipoplexes bound at the cell surface, cells were treated with 1 mL glycine (0.2 M, pH = 2.8) for 30 min at 4°C and rinsed in ice cold PBS before FACS analysis [26], [27].

Ferri-siderophore complexes are bound at the cell surface by specific outer membrane receptors and transported into the periplasm, where a periplasmic binding protein delivers the complex to an inner membrane transporter [5].

Plg bound at the cell surface may then be activated to pln by cell-surface or possibly stromal cell-derived [ 43- 46] uPA.

Following the transfection, the cells were washed three times with heparin (200 μL; 2 mg/mL) for 1 h to remove the DNA complexes bound at the cell surface.

A processing pathway in which the full-length mature enzyme is bound at the cell surface and cleaved to generate both identified truncated forms by membrane-type 4-MMP (MT4-MMP, also termed MMP-17) has been proposed [ 85].

After incubation at 4°C alone, the gD antibody remained bound at the cell surface and was detected in clathrin-coated pits, but following incubation at 37°C it was retrieved into endocytic tubules and membranes wrapping HSV1 capsids, confirming that gD from the PM ended up in the virus envelope.

Since the amount of Ga or Cr in TC137 (with YxeB) was the same as the amount in TC111 (no YxeB), the Ga and Cr levels of the wild-type strains represent imported metal-siderophore, not metal-siderophore bound at the cell surface by YxeB.

Alternatively, secreted IL-6 can bind to the soluble IL-6 receptor (sIL-6R), which then binds gp130 at the cell surface and initiates intracellular signaling.