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For example, added to norovirus-like particles, citrate precisely binds at the binding pocket on the histo-blood group antigens involved in attaching to host ligands, preventing the transmission of these viruses, as well as reducing symptoms in those already infected with noroviruses [28].
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Ketamine is a noncompetitive antagonist of the NMDAR that binds at the polyamine-binding site.
Molecular docking studies and competitive binding assay indicated that 5m effectively bind at the colchicine binding site of the tubulin.
The observed binding modes suggested that all three compounds bind at the ligand binding site of IL-2.
The results showed that the xenobiotics bind at the substrate binding site.
Docking studies revealed that these conjugates interact and bind at the colchicine binding site of the tubulin.
Most inhibitors are folate-analogs that bind at the folate binding site and are not species specific.
Molecular modelling studies suggest that these compounds might bind at the peripheral binding site of AChE, which opens the possibility to design inhibitors able to bind at both, the catalytic and peripheral binding sites of the enzyme.
This suggests the probable mechanism by which the bulky K+ with five water molecules bound at the upper binding site at 145.10 ns.
As an example, compound 2 (a non-TA compound) was shown to bind at the TA binding site.
Additionally, Figure S3 (Supporting Information) shows the superimposition with the CRY protein structure containing FBXL3 protein bound at the FAD binding site, (PDB ID: 4I6J 5).
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