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Such binding prevents RNA polymerase, which initially binds at the adjacent promoter, from moving into the coding region.
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Also, we wished to determine whether the interaction between NF-κB binding at the κB6 site, with proteins bound at the adjacent CREB/ATF site and/or upstream κB3-5 sites, was necessary for Iγ1 expression in both Ramos B cells and as an extension, primary B cells.
LFn binds at the junction of adjacent PA63 subunits, with each subunit making unique contacts with the ligand.
In addition to chromodomain binding to the histone tail, AT-Hook/ATHL can bind to the adjacent site in the minor groove of DNA, sandwiching the DNA between PC and histone surface (see Additional file 8).
Because MDC1 directly binds to the adjacent pSer139 of H2AX (γH2AX), the dephosphorylation of pTyr142 could be directly coupled with MDC1.
Recent findings suggest that histone ejection may occur not at the nucleosome that is directly bound by the SWI/SNF complex but rather at the adjacent nucleosome following the repositioning of the bound nucleosome [63].
We provide evidence that oligomerization is mediated by amino- and C-terminal arms that bind to the adjacent monomers.
However, we favour a direct role, because we find that Fun30 binds at the silent HMR locus, and less so to the adjacent euchromatic region.
The RdRP then binds to the 5' end of the genome in order to initiate negative strand RNA synthesis at the adjacent 3' end of the genome.
Guests also have privileges at the adjacent Torrey Pines Golf Course.
Generation at the adjacent coal station is unaffected.
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