Sentence examples for binds as a tetramer from inspiring English sources

Mnt binds as a tetramer to a palindromic binding site.

It binds as a tetramer to a symmetric binding site and, in earlier work, all single base changes to the consensus site were synthesized and their change in binding affinity measured.

GRH binds to DNA as a dimer, whereas LSF binds as a tetramer [ 17, 18].

The model TetR from E. coli binds as a dimer to a 15 bp palindrome while QacR from S. aureus binds as a tetramer to a 28 bp palindrome [ 3].

In particular, Soldaini et al. [ 6] examine the spacing between two Stat5a homodimers when bound as a tetramer.

As a transcription factor, p53 binds DNA as a tetramer, and mixed expression of WTp53 and ΔNp53 was key to the accelerated aging phenotype.

The domain in the C-terminal region enables oligomerization of p53 protein, which binds to DNA as a tetramer.

Specifically, in the absence of DNA, loop L1 of the p53 DNA binding domain adopts an extended conformation, whereas two p53 subunits switch to a recessed loop L1 conformation when bound to DNA as a tetramer.

p53 binds its target sites as a tetramer [3] [6], and it is presumed that this is the case for p63 and p73.

p53 is a transcription factor that binds directly and specifically as a tetramer to target sequences of DNA (p53-responsive elements (p53RE)) (El-Deiry et al, 1992; Funk et al, 1992; Bourdon et al, 1997).

Nob1 is predicted to have similar dimensions and was reported to bind RNA in vitro as a tetramer (Lamanna and Karbstein, 2009).