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The POU domain of Oct-4 is a conserved DNA-binding domain that binds as a monomer to the octamer sequence motif, 5′-ATGCAAAT-3′ (Botquin et al, 1998).
Based on our cloning results using the yeast one-hybrid system, we discovered that the mouse homologue of human LXRalpha binds to the CNRE and demonstrated that it binds as a monomer.
It is suspected that XlnR binds as a monomer [ 1].
MuA binds as a monomer to each L/R site, introducing an 80° to 90° bend (Kuo et al. 1991).
CpoB is a trimer under the conditions used (Krachler et al., 2010), but it is unclear whether CpoB binds as a monomer and/or trimer to PBP1B.
In Figure 5, the SPR signal for DB1255 ATGA complex formation is half that produced by DB293 and shows that DB1255 binds as a monomer compared to the stacked dimer formed by DB293 in the ATGA minor groove.
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The yeast HXT (glucose transporter gene) repressor Rgt1 lacks a dimerization domain and thus appears to bind as a monomer to its consensus binding site sequence (5′-CGGANNA-3′).
In the FR region, the binding sites present are octamer-like; hence Oct-2 is assumed to bind as a monomer.
Lambda repressor cleaves itself at the peptide bond between Ala111 and Gly112, but only when bound as a monomer to the RecA-ssDNA-ATP filament.
16 TNF-α is active as a homotrimer, but it is also found bound as a monomer, dimer or trimer to the surface of TNF-α-producing cells.
Ubiquitin is a small ubiquitous 76 amino acid polypeptide which is covalently bound as a monomer (monoubiquitin) to proteins or as a Ub polymer (polyubiquitin).
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