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Once a protein encounters and binds a segment of DNA, be it a specific sequence and/or a preferred structure, the resulting protein DNA complex becomes a distinct entity.
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A unit in which a molecule of a histone is bound to a segment of the DNA chain of genetic material is termed a nucleosome.
RNA interference: Cutting mRNA The small interfering RNA will bind to a segment of messenger RNA that matches its sequence, triggering the messenger RNA to split and rendering it useless.
Signal molecules bind to a segment of the receptor called the extracellular domain that faces out from the cell.
The enzyme binds a DNA segment of ∼130 bp, which is wrapped around the A2B2 complex.
Here we show that with approximately 200-fold higher affinity than for the mu opioid receptor, naloxone binds a pentapeptide segment of the scaffolding protein filamin A, known to interact with the mu opioid receptor, to disrupt its chronic opioid-induced Gs coupling.
Akiyama, Mizuno et al. propose that the β-hairpin-like loop of the RseP enzyme binds the transmembrane segment of a substrate and presents it to the active site.
Second, Hsc70 binds a C-terminal segment of the heavy chain within a funnel of surrounding protein (largely from the ankles and terminal domains of adjacent triskelions).
To confirm if NFκB binds to this segment of BLK we performed a CHiP-qtPCR experiment in a human Daudi cell line (figure 3A C).
In the currently accepted model [9], the open enzyme clamp binds a DNA segment termed the 'gate' or G-segment.
The breakage-reunion domain binds a DNA segment termed the 'gate' or G-segment at the DNA-gate.
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