Heparin binds a multitude of growth factors and maintains their bioactivity for an extended period of time.
The c-myc product, Myc, is a transcription factor that binds a multitude of genomic sites, estimated to be over 10 15% of all promoter regions.
Our results show that wt p53 binds a multitude of promoter sequences causing increases in histone H3 and H4 acetylation.
These novel diagnostic agents produce high contrast images due to their fast clearance from the bloodstream and healthy tissues, can be evolved to bind a multitude of cancer biomarkers, and are easily functionalized by site-specific bioconjugation methods.
HS chains, unique in their ability to bind a multitude of proteins, ensure that a wide variety of bioactive molecules bind to the cell surface and ECM and thereby function in the control of diverse normal and pathological processes [1], [4], [5].
These proteins are able to bind a multitude of different signaling proteins including kinases, phosphatases and transmembrane receptors and play a major role in modulating a wide range of regulatory processes such as mitogenic signal transduction, cell cycle control, ion channel regulation, and apoptosis [36].
Because RBM44 carries an RNA recognition motif (RRM) and the RRM could potentially bind a multitude of RNA sequences and proteins (reviewed in reference [29]), we suspect that RBM44 may function as an RNA-binding protein required for intercellular bridge function.
A striking feature of the 14-3-3 14-3-3 14-3-3heir ability to bind a multitude of functionally diverse signaling proteins, iscluding kinases, phosphatheir, abilitynsmembrane receptors.
Another way in which p300/CBP is able to respond to signaling pathways is due to the ability of p300/CBP to bind a multitude of different proteins, using its various protein-interacting domains.
As the mobile liquid phase slowly percolates through the stationary column, each As III) solute progressively binds to a multitude of Fe III) sorption sites favoring As III) oxidation.
MIP controls the intracellular levels of PI[ 3, 5]P2, which in turn binds to a multitude of proteins [ 28- 30], therefore working as a principal molecule in the coordination of intracellular networks [ 28, 31].
