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This model predicts that the combination of both antibodies would inhibit signaling induced by either class of Wnt isoforms since, although LRP6 dimerization would likely still occur, Wnt binding would be blocked by one or the other antibody.
Similar(59)
In the cis conformation the nSH3 binding surface would be blocked by P238 and other residues from the cSH3 acting as a "reversible lid" ([ 40]; reviewed in [ 41]).
In the first case, NFκB would be blocked by binding to PARP-1 and this union would be disrupted by PARP-1 auto-poly(ADP-ribosyl)ation [ 18].
Since these binding data are similar to those of our less selective compounds, A2A and also A1 receptors would be blocked in these studies.
Access routes would be blocked.
He'd been blocked.
Virus binding could be blocked with unlabeled M. amurensis lectin.
Unspecific tetramer binding could not be blocked by CD8α antibody.
Nonspecific binding sites were blocked with TBST/3% milk powder.
Nonspecific protein binding sites were blocked with serum-free protein blocking solution.
Non-specific binding sites were blocked with goat serum.
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