Sentence examples for binding with the substrate from inspiring English sources

Also, as collagenase is a zinc-containing metalloproteinase, the catechins within the tea extract which are known to be metal chelators may bind to the Zn2+ ion within the enzyme thus preventing it from binding with the substrate [ 10].

This is when the cell adhesion molecules are binding with the substrate.

The films formed by EPD were improved binding with the substrate by anodization under high voltages with sparking, and then the anodic films consisted of Si Mg or Ti Si Mg composite oxides.

The nature of amino acids present at the CBM determines the specificity of binding with the substrate.

Four conserved amino acids identified in this study are proposed to be essential for binding with the substrate and they form two distinguishable sequence motifs.

Furthermore, it has been suggested that the N-terminal 14 residues of the E protein are not involved in binding with the substrate F, and in the PscE-PscF-PscG complex, only the residue Met2 of PscE interacts with PscF [21].

Comparisons of our ternary SK ADP shikimate complex with an earlier binary SK ADP complex show that conformational changes occur on shikimate binding with the substrate-binding domain rotating by 10°.

The regions of greatest non-complementarity between the enzyme and ligands are the portions of the ligand that make few polar contacts with the binding site, as well as the sites of chemical reaction, where overly strong electrostatic binding interactions with the substrate could hinder catalysis.

A basis for the regulation of threonine deaminase by heterotropic effectors has been studied by capitalizing on the intrinsic fluorescence of the essential pyridoxal phosphate cofactor in this enzyme in kinetic and equilibrium binding studies with the substrate analog D-threonine.

The design was successful in creating strong hydrophobic binding interactions with the substrate, which parallels lessons from simple micelle systems.

Interestingly, it was found that DENV 2′OMTase activity and binding increases with the substrate chain length until they reach a plateau at n = 5.