Sentence examples for binding with the mRNA from inspiring English sources

All regions of miRNA are important for binding with the mRNA.

The scripts to calculate the free energies of the 16S rRNA tail binding with the mRNA were downloaded from http://sourceforge.net/projects/free2bind/ and included in our Perl scripts.

Mouse ES cells lacking Mettl3 and Mettl14 lost self-renewal capability and the decreased levels of mA in mRNAs of developmental regulators correlated with binding of the mRNA stabilizer HUR, indicating that mA methylation inversely correlated with mRNA stability and is needed to maintain pluripotency [ 52].

In the case of Dim1 and Tsr1, these are conserved to E. coli and in both bacterial and eukaryotic ribosomes are incompatible with binding to the mRNA, 60S subunit, initiator tRNA and translation factors.

Translation initiation occurs with a ribosome binding to the mRNA template and begins at the start codon with incorporation of the first amino acid of the polypeptide.

One model proposes that miRISC competes with eIF4E for binding to the mRNA 5′ cap structure and thereby blocks 40S subunit recruitment.

One probable explanation for this trend is that longer sequences have more alternative regulatory mechanisms (such as miRNA binding) that are associated with the mRNA translation process.

Thus, the binding of the miRNA with the mRNA occurs over the entire nucleotide sequence, not only within the "seed" region.

eIF4E is a cap-binding protein that interacts with the mRNA 5'-cap structure, m7GpppN (where N is any nucleotide).

An alternative approach is to fuse GFP to an RNA-binding protein that associates with the mRNA of interest, and ZBP-1-GFP and Exu-GFP have been used in this way to track β-actin and bcd mRNA movements (Oleynikov and Singer, 2003; Theurkauf and Hazelrigg, 1998).

This variability may indicate the importance of the GU dinucleotide in enhancing the binding of miR156a with the mRNAs.