Sentence examples for binding with the linker from inspiring English sources

They can also directly decompact chromatin and compete for chromatin binding with the linker histone H1.

BADGE was then conjugated to the nanoparticle via its epoxide, binding with the PEG linker's terminal amine group; 100 μL of 10 μM of BADGE in 10 mM HEPES was added dropwise to the nanoprobe solution under vigorous stirring and allowed to react overnight.

However, in both inhibitor binding pockets, the linker oxygen and nitrogen atoms do not appear to make hydrogen bond interactions with TTR.

Third, the binding of the linker histone H1 to linker DNA greatly affects chromatin folding and condensation.

Some of the isolated aptamers also showed some binding to the linker.

The cross-linking process occurs with the formation of cross-binding between the linker molecule and polymer chains.

The thiol must be connected to hapten without interfering with hapten binding, with linkers facing outwards of the binding pocket.

Neither chemoselective conjugation nor antigen binding was impaired with the sulfone linker.

Hence, binding sites present on the linker DNA are largely the active binding sites available to interact with the proteins to form protein complexes.

The similarity of compound 2a to 2b and 1 with respect to structure and binding strength, differing only in the linker to the acrylamide binding group, is further evidence that that it is the covalent binding property that determines the difference in binding kinetics, rather than e.g. a slow conformational change of the target enzymes.

Lanes 1 and 3 served as control lanes, so that any non-specific binding that occurred with the cross-linkers, rather than the protein, could be subtracted from the final RU (resonance units) in the experimental lane.