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Positron emission tomography offers the potential of imaging radiolabelled-annexin V binding with high sensitivity and resolution (temporal and spatial).
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Such endeavors require excellent molecular binding performance, with high sensitivity, selectivity, and low signal to noise ratio.
So, we can agree that Sgc8-FSNPs specially recognize and bind CEM with high sensitivity, which is attributed to the interaction between aptamer and its targeting cells rather than the nonspecific binding between FSNPs and cells.
Radioligand-binding studies provide excellent quantitative data with high sensitivity, but are time-consuming, laborious and lack the possibility of high spatial and temporal data acquisition [16].
Protein-deoxyribonucleic acid (DNA) interactions, such as transcription factor-DNA binding, DNA methylation, or methylation/acetylation of histone tails, can nowadays be identified with high sensitivity and specificity, using next-generation sequencing (NGS) technology.
Ex vivo autoradiography allowed the direct assessment of 111In-LIBS target binding after exposure to arterial flow conditions and natural elimination from the blood pool with high sensitivity [24].
VSRH: vertical component with high sensitivity, VSRL: vertical component with low sensitivity.
CE-SDS can analyze samples rapidly and with high sensitivity.
With high sensitivity, specificity is very low.
A POCT with high sensitivity and specificity was desired.
Thus not all kinetic parameters are identified with high sensitivity.
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