Exact(3)
Though Eu III) prefers ionic binding with a strong acid ligand, it is also capable of weak binding with a neutral oxygen donor at pH 3 and 4. Sorption is affected by solution acidity despite the absence of ion exchange.
In addition, the thermodynamic signature of the interaction is the same as that usually found for this type of binding, with a strong enthalpy entropy compensation for all the mutants.
In contrast to the extended binding pattern of hnRNP C, U2AF65 displays more restricted binding, with a strong preference for the regions directly upstream of 3′ splice sites.
Similar(57)
Fluorescence is suppressed due to protonation of the chromophore upon anion binding, with a stronger level of interaction at low pH values.
The ble gene encodes binding protein with a strong affinity to the bleomycin family of antibiotics (Gennimata et al. 1996), which was included due to high incidence in screening initial isolates (9/10 S. aureus isolates).
Beclin 1 ECD defines a novel class of membrane-binding domain, with a strong preference for lipid membrane enriched with cardiolipin.
When the proliferative response to peptides was compared with their binding score, a strong correlation was seen (Fig. 3a).
Note also how the green PFAM domain (a cNMP-binding domain) coincides with a strong propensity for a number of beta-strands, which could indicate a globular structure stabilized by beta-sheets.
We found that the Ni II)–IDA complex 1-2Ni II) binds to the His6-tag (HHHHHH) with a strong binding affinity (Kd = 24 nM), the value of which is 16-fold higher than the conventional Ni II)–NTA complex (Kd = 390 nM).
A similar case was reported for TMPyP4 binding to a human c- kit proto-oncogene DNA G-quadruplex with a strong binding constant (K1) around 10, and a weak K2 around 10 [ 41].
It is assumed that one promiscuous T-epitope is present on this protein, which binds to three of the six MHC-II molecules for one human subject, with a strong binding affinity of 150 nmol/l.
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