Sentence examples for binding with a specific from inspiring English sources

The complex of surface-immobilized DNA aptamer with fluorescent complementary oligonucleotide releases the oligonucleotide upon binding with a specific target, which is translated by a decrease in fluorescence.

These results demonstrate that an appropriate NBA unit in the peptide plays an important role in the RNA binding with a specific contact such as hydrogen bonding, and the interaction between the nucleobase in the peptide and the base in the RNA can enhance the RNA-binding affinity and specificity.

This shifts the populations to conformational states that are stabilized by binding with a specific RE sequence [ 29].

The molecule's effects are mediated by the binding with a specific receptor in both osteoblasts and renal tubular cells (Juppner et al 1991; Usdin et al 1999).

We deduced that the binding sites of the native protein FL-PID2 in its kinase domain might not be well exposed and binding with a specific ligand (for example, the elicitors from blast pathogens) would be required for its conformational change enabling PID2 to homodimerize and/or to interact with its substrate(s), such as OsPUB15.

The average affinity of a drug/target captures their typical binding behavior, which is valuable to predict the binding affinity with a specific target/drug.

Robust specific binding was observed in all four brain regions tested with cortex showing the highest specific binding with a specific/non-specific binding ratio of ~18.

We propose this to comprise a potential site for interaction of the effector-binding module with a specific DNA-binding domain, so as to mimic the organisation of the multi-domain transcription regulators.

A LIM domain mediates protein interactions and consists of a protein-binding motif with a specific three-dimensional structure comprising a double zinc finger [ 2].

Combinatorial sequence analysis of these co-regulated genes generated a hypothetical regulatory code consisting of Ets binding sites associated with a specific co-motif, ATTA.

Taslim et al. developed DIME that takes normalized differences of ChIP-seq counts in each genomic bin as input and used a finite mixture model (non-differential, negative/positive differential) to identify genes with differential binding for a specific protein in two conditions [ 18, 19].