Sentence examples for binding with a major from inspiring English sources

Int values were 8.7 kJ/mol in the case of HL intercalation into DNA, 6.3 kJ/mol in the case of its binding with a major DNA groove, and 3.6 kJ/mol in the case of its binding with a minor DNA groove.

Besides, the energy parameters showed that formation of strong hydrogen bonds inside HL+C60+DNA complex was possible only in the case of binding with a major groove of DNA, when the value of Hbnd was − 2.3 kJ/mol, in other types of interaction it was equal zero or − 1.0 kJ/mol (Table 1).

The binding of HL+C60 with a major DNA groove occurred via C-ATCC nucleotides (Fig. 4b).

eNOS (endothelial nitric oxide synthase) contains a MAPK (mitogen-activated protein kinase -binding site associated with a major eNOS control element.

Additionally, the helix-turn-helix DNA binding motif of IBP39 shows homology with TAF2 and its binding causes a major groove widening at TSS (Schumacher et al., 2003).

RanBP2, a Ran binding protein with four Ran binding domains, is a major cytosolic component of filaments that are derived from the cytoplasmic ring of the NPC during interphase.

Our findings showing the implication of both FbsA and FbsB proteins in the fibrinogen-binding ability of CC17 strains with a major role of FbsB are in contrast with previous reports suggesting that FbsA protein was the major fibrinogen-binding protein in the CC23 serotype III 6313 GBS strain [18], [20], [21].

Fig. 4 Combined interaction of diphenyl-N- trichloroacetyl -amidophosphate (HL) andiphenyl-N- trichloroacetyl -amidophosphateversions): a, b bindiphenyl-N- trichloroacetyl -amidophosphateercalation into minor andiphenyl-N- trichloroacetyl -amidophosphate

Fig. 3 Interaction of diphenyl-N- trichloroacetyl -amidophosphate (HL) with diphenyl-N- trichloroacetyl -amidophosphateajor grooves; c intercalation into a minor groove.

Concentrating on the Kv2.1-C1a peptide, we aimed at evaluating its profile of binding with the major protein components of the exocytotic machinery.

The systematic manipulation of binding sites remains a major challenge.