Sentence examples for binding with a high from inspiring English sources

Interactions with Arg2 of the peptide and Leu941 [Figure 8A] of JMJD2A-tudor also favour binding with a high contribution to the total free energy of binding.

It detected p50 binding with a high Z′-factor and a dose response analysis was carried out with two types of inhibitor (EB and -DHMEQ).

PFP predicted only two correct terms, GO 0005524 (ATP binding) with a high score and GO 0000027 (ribosomal large subunit assembly) with a low score, while PSI-BLAST, FFPred, and PFAM only predicted GO 0005524 among the five correct terms.

More recently, coupling ChIP with NGS (ChIP-Seq; Figure 3) [ 86] has become the de facto standard as it provides an unbiased, genome-wide look at enhancer binding with a high signal to noise ratio [ 87].

In particular, loop β1 β2 of the Tiam1/2 PH subdomains lacks the K- X n -K/R- X-R motif, which is characteristic in Akt, Btk and Grp1 PH domains that exhibit canonical PI binding with a high affinity using loops β1 β2 and β3 β4.

The model predicts H1 ligand binding with a higher degree of external predictability compared to a previously reported model.

This finding suggests that the IgM isotype introduces the potential of multivalent binding, allowing oligomers to bind with a high affinity, while monomers and dimers bind only transiently with fast off-rate kinetics.

The XylF protein, also known as XBP (xylose binding protein), is a periplasmic sugar binding protein with a high affinity for d-xylose [ 19].

Thus, proximity of a binding site with a high level of heterodimer occupancy to a TSS significantly increases the likelihood that an adjacent gene will be up-regulated by PPARγ activation.

Our aim is to identify only binding pockets with a high affinity for aromatic groups, in which case a lower benzene concentration is more selective.

Annexin V is a Ca2+-dependent phospholipid binding protein with a high affinity for PS [ 35, 53, 59] and is used when conjugated to a fluorochrome (FITC) as an indicator of early apoptosis [ 8, 62].