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An observed decrease in the level of diflunisal binding with a corresponding marked increase in the level of Congo red binding of HMW TTR surfaces was also measured.
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Moreover, changes in the intrinsic protein fluorescence as a function of the pentose phosphate sugar concentration demonstrated co-operativity in Pdx1 upon binding this substrate, with a corresponding Hill coefficient of approximately 3.3 [21].
Likewise, strong binding was observed with a corresponding small peptide (S262 to P) spanning the A.m.H GBD, as well as with the N-terminally truncated A.m.H 4-1 construct (Fig. 3).
More specifically, we want to understand the origin of α = 350-fold enhancement (positive heterotropic linkage) of binding of SNF to either SLIV or U2A′ (upon binding by the other) with a corresponding free energy (Δ g°) of −3.5 kcal/mol.
Finally, candidate cryptic sites encompass all sites with higher affinity for binding than a corresponding natural site based on comparison of their respective Ri values (see below).
Although sequence alignment revealed several conserved residues within the N terminus calmodulin-binding domain of Orai1 with a corresponding stretch in Orai3, the N terminus of Orai3 is considerably shorter than Orai1.
V is the fraction of time that an operator is bound by one particular TF out of all possible TFs with a corresponding binding sequence (no).
The presence of signals at dot 4 suggests that the tissues of transgenic carrot storage roots contain a functional CFP10 protein capable of binding with the corresponding polyclonal antibodies to the rCFP10, produced by E. coli. Figure 5 shows the EIA data for the recombinant ESAT6 antigens synthesized in transgenic carrot tissues (lane 1) and E. coli (lane 2).
Stimulation of TLRs by binding with corresponding ligands triggers at least two distinct signaling pathways: an MyD88-dependent pathway and an MyD88-independent pathway.
For these cases, the pK's are assumed to be infinite (no binding) with corresponding dissociation constants equal to zero.
Accounting for these dissimilarities in the model would require variation of parameters of ER binding with ERE and corresponding rate constants of transcriptional activation.
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