Sentence examples for binding while the double from inspiring English sources

The L2309A or L2323A mutations led to a small but reproducible increase in binding, while the double mutant (L2309A/L2323A) showed a larger increase in binding (154% that of wild type; Figure 3F).

Mutation of the downstream putative GABP site had no effect on recombinant GABP alpha/beta binding, while the double mutant also resulted in the loss of GABP alpha/beta binding.

Bulk experiments showed that Doc mutants Q1 and Q3, originally designed to suppress one of the binding modes, were still able to bind Coh with high affinity, while the double knockout did not bind.

Site 1 mutants, S209A and G210R, showed a complete loss of binding while the binding of site 1 double mutant K204A/L208A was not significantly reduced.

Further site-directed mutagenesis analysis revealed that His418 and Ser420 had little effect on metalloid binding while the C172A single mutant and C172A/H453A double mutant exhibited significantly decreased affinity for SbIII, suggesting that C172 is the third residue that participates in high-affinity binding.

Intercalating agent action depends on molecules chemistry and on the binding site at the double helix.

This arrangement of two nucleotides binding together across the double helix is called a base pair.

Surprisingly, RNA binding by the double-stranded RNA binding domain (dsRBD) is dispensable for Dcr1 function, while zinc coordination of the extended dsRBD is required for its nuclear localization and RNA silencing.

These results suggest that Arg at position 73 is involved in LTB4 binding, while the involvement of Arg at position 53 seems enhanced in the frame of the double mutant configuration (R53T/R73A).

The C-terminal aa465 aa526 also exhibited weak binding, while the N-terminal aa1 aa267 did not show detectable binding activity.

The trade provisions of the TPP are binding while the provisions of the COP21 climate agreement are not.