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The mechanism of action of IVIg is unclear, but studies suggest blockage of the Fc receptors of the reticuloendothelial cells and suppression of antibody production and binding which may be a result of anti-idiotype antibodies that bind antiplatelet antibodies and modulate the immune response [ 14].
Filter-binding studies demonstrated that the addition of Mg2+ inhibits TRAP binding, which may be partially due to the effect of Mg2+ on RNA tertiary structure formation.
These results are suggestive of multivalent binding, which may be due to increased residence times for monovalently bound CCK4 constructs on the cell surface relative to MSH4 constructs, the greater residence time being necessary for the establishment of multivalent binding.
The energy difference of 2.79 kcal·mol−1 between lower and upper binding sites in sim-K1 indicated that the lower binding site was more energetically favorable for K+ binding, which may be the reason that the K+ in sim-K2 finally located at the lower binding site.
We demonstrate the structural dynamics which accompany spike-receptor binding, which may be involved in triggering membrane fusion.
This nucleotide variant has been shown to affect OCTamer-binding transcription factor-4 (OCT4) binding, which may be necessary for maintaining the unmethylated state of the maternal allele.
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We suggest that the D1 agonists bind deeper in the binding site, which may be a consequence of interactions with Ser1073.36.
Local alignment is not well-suited to detect lower affinity binding sites, which may be distant in sequence space yet functional; nor can it capture the rapid turnover of binding sites, which often occurs without conservation of position (Dermitzakis and Clark, 2002; Ludwig, 2002; Tautz, 2000; Wray, 2003).
Thus, compared to conventional liposomes, liposomes made from fluoroalkylated PCs have different binding properties, which may be relevant to their use as drug carriers.
ZNFx play a role in diverse functions including lipid binding [44], which may be relevant in camel as camel uses extensive reservoirs of fat to adapt to its environment.
Quantification of Tspan9 expression levels on platelets may provide clues as to potential binding partners, which may be expressed at similar levels.
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