Sentence examples for binding which is not from inspiring English sources

Moreover, optimal contracts can include a boundary part (i.e., the endogenous, type dependent participation constraint is binding), which is not a copy of the outside option of no contract.

Repeated D-amphetamine treatment significantly increased PDE10A binding, which is not observed upon selective D1 receptor blocking.

However, SA/avidin is immunogenic, and endogenous biotin levels (10 8 10 7 M) can affect the efficacy of SA binding, which is not favorable for clinical use.

The observation was rationalized by the extra entropic cost associated with reorientation of the F296 and Y375 side chains upon "normal" substrate binding, which is not necessary in the "flipped" mode.

However, we also failed to detect Sds21 at the late-firing Rif1-associated origin ori2-4451: is is possible that our PCR primers in this case are simply located in an area of low or absent Rif1 binding, which is not homogeneously distributed over late-firing regions (Hayano et al., 2012).

Such findings serve to emphasise that very subtle alterations in amino acid residues can have major implications on drug binding efficacy and highlight the importance of understanding the structural basis of drug binding, which is not always apparent from analysis of DNA sequences.

To predict the effects of novel SNPs on miRNA target binding, which are not included in the current database, we provided three flexible online tools in miRNASNP v2.0.

Subsequent addition of exogenous uPA caused a further approximately 37% increase in plg binding, which was not observed with the addition of PMSF-uPA.

On the other hand, when considering the unliganded enzymes and in the absence of large changes in protein conformation that would be unexpected for this point mutation, W203Y would be assumed to be the most hydrated because of phenol's polarity and potential for forming hydrogen bonds; this would have resulted in less exothermic binding, which was not observed.

However, a previous study of the heart from our laboratory [ 20] used the same methodological strategies as the present study, and identified cardiac changes related to lipid metabolism, oxidoreductase activity and calcium ion binding which were not found in the lung in the present study.

Only the books' bindings (which are not original) were damaged.