Sentence examples for binding which is dependent from inspiring English sources

Effective affinity optimization requires an accurate theoretical understanding of the free energy associated with binding, which is dependent on bonding (solvation and intermolecular interactions) and the conformations of the receptor ligand assembly (before and after binding).

The possible mechanism for increasing plasma LDL-C levels by fish oil in hamsters may be partially due to decreased hepatic LDL-receptor binding which was dependent on the dietary cholesterol content [ 18].

These derivatives have been shown to exhibit novel anion binding behaviour which is dependent on their interlocked nature, a feature which has further been exploited by the incorporation of signalling groups to sense the anion binding event.

Although the exact molecular mechanism by which this polymorphism may affect the risk of GBC development is still unclear, studies in the PTGS2 promoter revealed that PTGS2 transcription is activated by E2 promoter binding factor 1 (E2F1) [47], which is dependent on the transactivation and DNA-binding domains of E2F1 [48].

Drug distribution from blood vessels within tumors depends on diffusion and and/or convection, and is inhibited by consumption in proximal cells [ 23, 25- 27]; for monoclonal antibodies consumption is due to binding to the receptor target, which is dependent on antibody dose, number of antigenic targets per cell, and the affinity of the antibody for its target [ 28].

Previous data has demonstrated that fibroblasts have an increased adherence to 3DG-collagen, which is dependent on binding by α1β1 integrin [28].

: The factor limiting this process is the amount of energy that is released through fusion, which is dependent on the binding energy that holds together these atomic nuclei.

As a result, uptake (which is dependent on the occurrence of binding) is also optimized.

In this assay, binding of the dCas9 complex to the DNA yields a FRET signal between the donor (Cy3) and acceptor (Cy5), the magnitude of which is dependent on its conformational state (Fig. 4b and Supplementary Fig. 12).

The ratio data were then randomized 20 times to evaluate the probability of false positives, allowing the assignment of likely ORC1/CDC6 binding and sites, which were dependent on specified FDRs of ≤0.05 (5% of sites will be incorrect), 0.05 0.1 (5%10%% incorrect), and 0.1 0.2 (10%20%% incorrect).

Similar to CCL1 and CCL2, CGL1 and its isogalectin CGL2 (CC1G_05005) showed toxicity against C. elegans which was dependent on binding to a Galβ1,4Fucα1,6-epitope Galβ1,4Fucα1,6-epitopeent in the wonm intestine [ 35].