Sentence examples for binding which can explain from inspiring English sources

One of the three N-Hcy-lysine residues in Fbg from homocystinuric patients, N-Hcy-Lys562, is located in an unstructured region (α392-610) of the α-chain known to be involved in tPA and plasminogen binding, which can explain the abnormal characteristics of fibrin clots formed from N-Hcy-Fbg (Jakubowski 2013; Sikora et al. 2014).

Along these lines it is plausible that when Ire1 is monomeric, the -boxes of individual Ire1 molecules may not sustain RNA binding, which can explain the lack of mRNA recruitment under non-ER-stress conditions (Aragón et al., 2009; Figure 3D).

Further functional analysis in breast cells revealed three cis-acting variants affecting the binding of transcription factors which can explain at least in part the differences in expression level associated with the expression haplotypes.

In addition, the model suggests a general mechanism for hormone action based on metabolically regulated differential and cooperative protein receptor binding events in cellular compartments which can explain agonism, antagonism and potentiation within the framework of receptor occupancy theory.

The aim of the current work is the discovery of novel drug-leads and the formulation of structure-function relationships which can explain the selectivity of ligand binding to the NAD+ pocket.

Notably, rearrangement of the NPxxY motif network of interactions changes the position of helices, which can explain the loss of the water binding site between helices 7 and 1 (cluster 3 in Table 2).

The direct coating of proteins can lead to a partial denaturation [44], which can explain the selection of scFv antibody clones binding only to linear epitopes of Crf2.

The first issue, which can explain failure in identification of 6 lower abundance species, is the bias associated with binding PCR primers to target-template DNA in a mixture.

There are several hypotheses which can explain this propensity.

Docking studies were performed to give suggesting binding modes which can well explain their impacts on the enzyme.

Interestingly, the indirubin E804 complex exhibits two binding modes which can be explained by the near-symmetrical core scaffold.