Sentence examples for binding were assumed to from inspiring English sources
Bmax and Kd values of [H]Paroxetine binding were assumed to represent SERT density and ligand binding affinity, respectively, whereas Vmax and Km values of [H]Serotonin uptake were taken as estimates of SERT rate and affinity, respectively.
Therefore, one can frequently find the hypothesis that within a congeneric series of closely related ligand analogs the entropic contribution to binding is assumed to be equivalent.
The profiles characterizing DNA protein binding are assumed to be defined throughout the sites.
Ligand-TF and TF-operator binding are assumed to be fast processes and set to quasi steady state.
Ligand binding is assumed to unidirectionally influence the phosphorylation of the two regarded intracellular domains [ 36, 28].
In contrast, nitrogenous base binding was assumed to be thermodynamically unfavorable, with a respective equilibrium constant = k bind / k diss << 1.
Known sites of condensin binding are assumed to coalesce into one complex temporarily if they come within 40 nm of each other, the capture radius consistent with the physical dimension of condensin.
The influence of protein binding on disposition of chemicals has only been investigated in SBSP models using the explicit relationship described by eq 14. (2110) As the first approximation, protein binding was assumed to be dependent on lipophilicity, according to eq 4 in section.
The boundaries of the binding box were assumed to be known and directly derived from co-crystallized ligand coordinates.
The expressions of targets and non-targets were modeled by a two-component Gaussian mixture distribution, and the nucleotide frequencies at each position of an extended binding motif were assumed to be multinomial which was represented by a position specific weight matrix (PSWM).
