Sentence examples for binding we postulated that from inspiring English sources

Since this domain may be involved in ligand binding, we postulated that the A438T variant might have decreased binding activity and signaling function.

Based on these findings we postulated that transcription factor binding motifs for C/EBPβ and AP-1, in addition to FoxO, would be enriched in the promoter regions of genes identified as indirect or direct targets of FoxO.

We postulated that anti-HIV-1 antibodies primarily bind monovalently because HIV's low spike density impedes bivalent binding through inter-spike crosslinking, and the spike structure prohibits bivalent binding through intra-spike crosslinking.

We postulate that binding of MMP-9 to collagen may adopt a sandwich conformation in which the collagen molecule closely interacts with the exosites of the enzyme including its long linker domain.

We postulate that inhibitor binding to viral capsid proteins leads to the prevention of virus adsorption and might also be responsible for the observed antiviral effect during and after adsorption.

We postulate that Phe-1353.36 of CXCR3 contributes to the binding by forming π π stacking interactions with VUF 10085, although this was untested by our mutagenesis study.

We postulate that HDV arose from the human transcriptome.

We postulate that mesenchymal stem cells participate in tissue repair.

On the basis of our observation that each Pellino has a different peptide binding profile, we postulated that Pellino1 selectively targets RIP1 over TRAF6, whereas Pellino3 is selective for TRAF6.

Because FAD can compete with both KL001 and FBXL3 for binding CRYs, we postulated that KL001 might inhibit CRY ubiquitination by occupying its cofactor pocket and impairing its association with FBXL3.

In summary, existing biochemical SAR is consistent with an essential role for all four polar atoms of the benzimidazole carboxamide scaffold in its binding to CHK2 and we postulated that alternative binding modes may better explain this SAR.