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Among the 1,146 genic promoters enriched for Jarid2 binding, we noticed a strong preference for genes critical in Wnt signaling (29 genes) and Wnt-related pathways.
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Our interest in 14-3-3 14-3-3 14-3-3l binding pastner for Cx43 was triggered when we noticed a non-canonical 14-3-3 binding motif and consensus serine potentiallation sites at the very C-terminus of Cx43 (Fig. 2e).
Interestingly, AP-2α promoter is dependent upon an initiator element for proper transcription, and we noticed a potential YY1 binding site at the transcription start site of the AP-2α gene (position +4) [ 33].
Although the loss of NCoR binding could play a role in the phenotypes we observe, we noticed a striking result when we compared the lifespans of previously published RTT models and the new R306C mice.
We noticed a general lack of sequence conservation and identified two subpopulations of las-specific binding sequences based on their distinct interactions with LasR [ 29].
"We noticed a different mentality".
"We noticed a downward trend," Mr. Lakefield said.
We noticed a few complications.
We noticed a different behavior for H3K36me3.
We noticed a MIR3 element (a SINE with Pol III promoter) that could be transcribed by Pol III and therefore might represent the target-binding site of MAF1.
We noticed a partial sensitization to cytarabine on MLH1 suppression.
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