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The characteristic blocking of the Ca2+ release channel in a closed state by 100 μM ryanodine was apparently preserved in this RyR2 mutant, but the Ca2+-dependent ryanodine binding was significantly changed compared with the other RyR2 types studied.
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A residue is in a hot spot if its free energy of binding is significantly changed (ΔΔ G≥ 2 kcal/mol) upon the mutation to alanine.
AP internal rotation was significantly changed.
Considering that both the anti-TF IgM level and SNA binding values were significantly changed in cancer patients and the respective changes showed quite an opposite direction, the same value of the SNA/anti-IgM index may be obtained if both variables are similarly either low or high.
In contrast, for TME3, no ethylene-responsive element binding factors were found to be significantly changed across any of the three timepoints, again supporting the collective evidence for other tolerant-related mechanisms in TME3.
The relaxivity (r1) of Gd ⋅1 is significantly changed when binding to zinc (Table 1).
Only the positions of single-stranded residues C74 and C75 and the associated amino acids of EF-Tu are significantly changed upon ribosome binding.
Two genes were significantly changed for Qfhs.ifa-5A and F. graminearum-treatment: Traes_5AL_5127CEB66 module B, flavin-containing monooxygenase) and Traes_5AL_A80AD7FF8 (module A, calmodulin-binding protein, Figure 5D).
You credit will be significantly changed.
Antithrombin III binding was significantly enhanced.
However, binding was significantly diminished for the ΔLinker4-5 construct.
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